TB – 500

What is TB-500 Fragment (17-23)?

TB-500 Fragment (17-23) represents the smallest active sequence of the thymosin beta-4 molecule that retains its actin-binding domain. Actin is integral to various cellular functions, including maintaining cell shape, facilitating movement, and supporting division. By interacting with actin, TB-500 Fragment (17-23) may influence cellular processes such as migration and proliferation. Research has focused on its potential roles in wound healing, inflammation modulation, and tissue regeneration. This peptide is intended exclusively for scientific investigation and is not approved for human or veterinary use.

Structure

• Chemical Formula: C36H66N10O13
• Synonyms: Fequesetide, Thymosin Beta-4(17-23), (17)(LKKTETQ)(23)

TB-500 Fragment (17-23) Research

The Role of Actin in Cell Function

Actin is a fundamental protein within eukaryotic cells, playing a pivotal role in maintaining cell shape, enabling movement, and facilitating division. It exists in two forms: monomeric (G-actin) and polymerized (F-actin). The dynamic equilibrium between these forms is crucial for cellular functions. TB-500 Fragment (17-23) has been observed to bind to actin, potentially influencing this balance and affecting processes such as cell migration and proliferation.

Thymosin Beta-4: Parent Molecule to TB-500 Fragment (17-23)

Thymosin beta-4 is a naturally occurring peptide present in many tissues. It is known for its actin-binding properties, which are essential for various cellular activities, including tissue regeneration and inflammation modulation. TB-500 Fragment (17-23) is derived from this parent molecule, retaining the active site responsible for actin interaction.

Thymosin Beta-4 Derivatives

Derivatives of thymosin beta-4, such as TB-500 Fragment (17-23), have been synthesized to focus on specific functional domains of the parent molecule. These derivatives are studied for their potential to selectively influence cellular processes like migration and proliferation, which are critical in tissue repair mechanisms.

TB-500 Fragment (17-23) and Healing

Research indicates that TB-500 Fragment (17-23) may play a role in tissue repair processes. Its interaction with actin could influence cell migration and proliferation, essential components of wound healing. Studies have explored its potential in promoting endothelial cell differentiation and angiogenesis, processes vital for effective tissue regeneration.

TB-500 Fragment (17-23) and Musculoskeletal Performance

In experimental models, TB-500 Fragment (17-23) has been investigated for its potential effects on musculoskeletal tissues. Its interaction with actin may influence muscle cell function and recovery processes, suggesting possible applications in studies related to muscle performance and repair.

TB-500 Fragment (17-23) and Inflammation

TB-500 Fragment (17-23) has been studied for its potential role in modulating inflammatory responses. By influencing actin dynamics, it may affect the behavior of inflammatory cells, potentially contributing to the regulation of inflammation in various tissue types.

TB-500 Fragment (17-23) and Cell Signaling

Actin plays a role in various cell signaling pathways. TB-500 Fragment (17-23)’s interaction with actin may influence these pathways, potentially affecting processes such as cell growth, differentiation, and response to external stimuli.

TB-500 Fragment (17-23) and Neurological Restoration

Emerging research has explored the potential effects of TB-500 Fragment (17-23) on neurological tissues. Its influence on cell migration and proliferation may have implications for studies focused on nerve regeneration and neurological recovery processes.

TB-500 Fragment (17-23): Summary

TB-500 Fragment (17-23) is a synthetic peptide derived from thymosin beta-4, focusing on its actin-binding domain. Research has investigated its potential roles in influencing cell migration, proliferation, and tissue repair processes. While studies are ongoing, TB-500 Fragment (17-23) continues to be a subject of interest in various fields of biomedical research.

Disclaimer

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

THIS PRODUCT IS INTENDED FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION.